n. [ L. vicissitudo, fr. vicis change, turn: cf. F. vicissitude. See Vicarious. ] [ 1913 Webster ]
God made two great lights . . .
To illuminate the earth and rule the day
In their vicissitude, and rule the night. Milton. [ 1913 Webster ]
This man had, after many vicissitudes of fortune, sunk at last into abject and hopeless poverty. Macaulay. [ 1913 Webster ]